Provenance record

AlphaGenome Atlas: A predictive map of every possible DNA letter change in the human genome

Google DeepMind (tier 1, lab) 2026-09-08T14:00:15.000Z Original ↗

Source note: Primary statements from a frontier lab.

Discourse valence

Mixed or uncertain

confidence 74% · 5 items · range -100 to +75

-100

-50

+50

+100

Adverse readingFavourable reading

Consensus of 5 models from different labs. Spread 175 points, agreement low.

AGI and timelines Biological and chemical uplift Existential and catastrophic risk

Excerpt as ingested

AlphaGenome Atlas maps the molecular effects of 9 billion single-letter DNA variants across the human genome.

Every model that read this

Model	Provider	Stage	Score	Conf.	Latency	Prompt	When
Llama 3.3 70B	Meta	analysis	0	70%	4525ms	v1.0.0 / m1.0.1	2026-09-10 09:18
GPT-4.1 mini	OpenAI	consensus	+25	80%	2542ms	v1.0.0 / m1.0.1	2026-09-10 12:19
Claude Sonnet 5	Anthropic	consensus	+35	40%	7558ms	v1.0.0 / m1.0.1	2026-09-10 12:19
Gemini 2.5 Flash	Google	consensus	-100	90%	2845ms	v1.0.0 / m1.0.1	2026-09-10 12:19
Mistral Small 3.1 24B	Mistral AI	consensus	+75	90%	4516ms	v1.0.0 / m1.0.1	2026-09-10 12:19

Llama 3.3 70B · reading

Maps DNA variants

evidence: primary horizon: n/a

GPT-4.1 mini · reading

Mapping the effects of every possible DNA letter change could significantly enhance genetic research and medicine, potentially improving disease understanding and treatment. However, the societal impact depends on how this information is applied, including privacy concerns and ethical issues, which introduces mixed implications.

evidence: primary horizon: near capability 70 societal 30 existential 5 economic 40

Claude Sonnet 5 · reading

This is a genuine scientific tool release with plausible medical research benefits, but the text gives no evidence of validation, adoption, or downstream impact. The implication for human flourishing is positive but currently speculative, resting only on the tool's existence and stated scope.

evidence: reported horizon: n/a

Gemini 2.5 Flash · reading

AlphaGenome Atlas provides a comprehensive map of DNA variants and their molecular effects. This tool significantly advances genomic understanding, enabling better disease prediction, diagnosis, and treatment. The primary implication is a positive impact on human health and scientific research.

evidence: reported horizon: n/a

Mistral Small 3.1 24B · reading

The mapping of 9 billion single-letter DNA variants provides extensive data on genetic variations. This can lead to significant advances in personalized medicine and genetic research.

evidence: primary horizon: n/a existential 0

Evidence extracted

AlphaGenome Atlas maps 9 billion single-letter DNA variants

The chain

SOURCE     Google DeepMind (tier 1)
   ↓
DOCUMENT   b73686f8-0b48-4e33-b94c-559c7ebe6fcc
           https://deepmind.google/blog/alphagenome-atlas-a-predictive-map-of-every-possible-dna-letter-change-in-the-human-genome
   ↓
EVIDENCE   1 extracted excerpt
   ↓
MODEL RUN  5 runs, methodology 1.0.1
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SCORE      +7  (Mixed or uncertain)
   ↓
CONFIDENCE 74%